Mineral trace elements and health - Iron
12 important questions on Mineral trace elements and health - Iron
How does iron play a role in energy production?
- Energy is produced via the breakdown of fats and carbohydrates to carbon dioxide and water.
- This breakdown occurs in special units within the cell called mitochondria and occurs via the activity of a special set of enzymes.
- Several of these enzymes need iron for their functioning, either because they contain a heme group or because they contain a so-called iron-sulfur cluster.
- Without iron our cells wouldn’t be able to carry out their function due to a lack of energy.
What are good sources of iron?
- food made from blood
- liver
- red meat
- beans and grains a bit
What type of iron is well absorbed?
and Fe3+ has to be converted to Fe2+ first
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How can you measur ethe amount of iron stored in the body?
- The more iron stored in the liver, the higher the amount of ferritin in the liver.
- What is unique about ferritin is that it spills over in the blood and can thus be measured in the serum.
- It so happens that the level of serum ferritin reflects the liver ferritin and thus the amount of iron stores in the body
What transports iron trough the body and from where to where?
What happens to people there ferrin with a high and a low amount of iron sotred in there body?
- When people have plenty of iron stored in the liver, the relative amount of iron bound to transferrin, called the transferrin saturation, is also high.
- When people do not ingest sufficient amounts of iron, initially their iron stores in liver are slowly emptied, resulting in a gradual decrease in serum ferritin.
What is iron recycling?
- After approximately 3-4 months, the red blood cells are broken down mainly in the spleen (milt) and the liberated iron is released into the blood, bound to transferrin and taken to the liver.
- The delivery of iron to the bone marrow for synthesis of red blood cells and the return of the iron to the liver from the spleen after dismantling the red blood cells is called iron recycling.
How much iron is lost on a daily basis?
but whimon who mestruate lose more iron
What is the RDA for iron?
8 mg for men
a lot more then we lose due to low absorption
The iron requirements are highest for pregnant women due to their rapidly expanding blood volume and the iron needed to support the growth of the embryo.
What happens is that when iron stores in liver are high?
- The liver releases a hormone called hepcidin.
- Hepcidin travels from the liver to the intestine, where it suppresses iron absorption by preventing the delivery of iron from the intestinal cell to transferrin.
- As discussed before, transferrin transports the iron from the intestine to the liver.
- As a consequence, the iron remains in the intestinal cells, which are eventually degraded, causing the release of its contents into the stools.
What happens is that when iron stores in liver are low?
When can you get when your body does not have enough iron?
symtomes: fatigue, weakness and low physical endurance.
The main cause of iron-deficiency anemia is consumption of a diet that is poor in (bioavailable) iron
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