Immunopathology of food allergy - Food allergens

3 important questions on Immunopathology of food allergy - Food allergens

65% of plant food allergens are part of 4 protein families/superfamilies

  1. Prolamin
  2. Cupin
  3. Bet v 1
  4. Profilin

What is the difference between class I and class II allergens?

  • Class I
    • reactivity to food allergens through the gastrointestinal tract
    • resistant to heat, degradation and digestion
    • higher potential to induce severe reactions
  • Class II
    • secondary sensitisation to cross-reactive food allergens mainly due to primary sensitisation to homologous pollen allergens via the respiratory tract
    • labile and easily degradable
    • often symptoms restricted to oral cavity

To which 3 families do animal derived food allergens belong to?

  1. Tropomyosins
  2. Parvalbumins
  3. Caseins

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