Biochemical aspects - Keeping allergens out, Basics of allergens
11 important questions on Biochemical aspects - Keeping allergens out, Basics of allergens
How much money do allergies cost in NL per year in 2016?
When can a protein become an allergen?
- It is considered foreign
- It is present in considerable amounts
- It is delivered during prolonged periods
Mention the 4 major plant allergen families
- Cupins: 7S and 11S-globulins
- Prolamins: LTP/2S-albumins
- PR-10
- Profilins
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Mention the 3 major animal allergen families
- Tropomyosins
- EF-hand parvalbumins
- Caseins
What is at the basis of the latex-fruit syndrome?
Can mass spectrometry measure the allergen structure of an allergen?
Does the basophil cell culture give a positive reaction when the allergenic protein only has 1 epitope?
What are advantages of IgE-based test?
- Cheap
- Easy
- Cross-reactions determination possible
What are disadvantages of IgE-based test?
- Too many false +/-
- Very limited clinical relevance
What are disadvantages of DBPCFC?
- Expensive
- Burdensome
- Not cross-reactivity determination yet
In which country is buckwheat labelled as an allergen?
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