Immunological aspects - Allergy I, etiology
6 important questions on Immunological aspects - Allergy I, etiology
How thick is the mucosal layer in the large and small intestine?
Small intestine --> thinner layer
In which 3 ways are food components absorbed in the gut?
- Very small molecules --> completely digested (proteins, monosaccharides) taken up directly by epithelial cells, passes into mucosa, used for energy
- Dendritic cells --> There is a DC population that has an extension that squeezes between 2 epithelial cells, this extension of cytoplasm can directly sample food stuff from the gut lumen, not having to pass through epithelial cells
- Large complexes (aggregates) --> taken up by M cells, situated on top of Peyer's patches. M cell absorbs material, passes it to another DC that activates T and B cells --> start of immune response
What is the problem in the leaky gut syndrome?
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Describe the process of DC maturation
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