Immunological aspects - Introduction & Definitions Basis immunology

7 important questions on Immunological aspects - Introduction & Definitions Basis immunology

What does a natural killer cell (NK) do?

It binds to a tumour, releases toxics and then gets out the way.

What does TLR stand for?

Toll-like receptor

Is TGF-beta pro-inflammatory or an anti-inflammatory cytokine?

Anti-inflammatory
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To which does a Helper T cell belong to? Innate or adaptive immunity?

Adaptive

By what is the cytokine IL-10 produced?

Treg

What can be done with immunotherapy, when the Treg are not functioning properly?

Boost the IL-10

What are 4 differences between primary and secondary response?

  1. Primary response: 10-14 days, Secondary response 5-7 days (faster)
  2. Secondary response 100x higher than primary, much more antibodies
  3. Primary --> IgM, secondary --> IgG
  4. During formation secondary immune response, cells are slightly changing structure of antibodies, trying to fit better the allergen. Binding strength/affinity increases

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