Blood - Red blood cells, formed by erythropoiesis, contain hemoglobin that transports respiratory gases - Relationship of RBC Structure to RBC Function

3 important questions on Blood - Red blood cells, formed by erythropoiesis, contain hemoglobin that transports respiratory gases - Relationship of RBC Structure to RBC Function

Describe the structure of an RBC

Biconcave disc with thin central region and thicker outer margin. Cytoplasmic surface consists of meshwork of flexible proteins.

How does the structure of RBCs (flexible mebrane and biconcave shape) aid in RBC function

  • Large SA:V ratio; faster exchange between interior and surrounding plasma.
  • RBCs can form stacks; stacks form and dissociate quickly that allow them to travel through narrow blood vessels.
  • Bend/flex in small capillaries; chaning shape allows them to squeeze through capillaries.

Why do RBCs have a short life span?

Mature RBCs are anucleate (no nucleus). They also contain no ribosomes. They cannot divide or synthesize structural proteins/enzymes -> Cannot repair themselves. Resulting in short life span of 120 days.

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