DNA replication - Bacterial DNA replication: chemistry and accuracy
5 important questions on DNA replication - Bacterial DNA replication: chemistry and accuracy
Where does the energy, needed for the attachment of new nucleotides, come from?
What is a processive enzyme?
Which subunit of DNA polymerase causes the enzyme to be processive?
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After DNA synthesis, only 1 mistake in 100 million nucleotides is made. What three factors play a role in this fidelity of DNA replication?
- The active site of DNA polymerase almost only attaches a new nucleotide when it is correct;
- DNA can identify a mismatched nucleotide and remove it (proofreading function).
What are ARS elements?
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