Extensions of Mendelian inheritance - Dominant and recessive alleles
10 important questions on Extensions of Mendelian inheritance - Dominant and recessive alleles
What are wild-type alleles?
What is genetic polymorphism?
Why are both of these colors considered to be wild type?
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What are mutant alleles?
Does a PP individual produce more of the protein encoded by the P gene than is necessary for the purple color?
How can a mutant allele be dominant over a wild-type allele?
- Gain-of-function mutations;
- Dominant-negative mutations;
- Haploinsufficiency.
What are gain-of-function mutations?
What are dominant-negative mutations?
What is incomplete penetrance?
Which individual(s) in this pedigree exhibit(s) the effect of incomplete penetrance?
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