Gene regulation in eukaryotes I: Transcriptional and translational regulation - The ENCODE project
6 important questions on Gene regulation in eukaryotes I: Transcriptional and translational regulation - The ENCODE project
What does ENCODE stand for?
What is the central goal of ENCODE?
What are 5 strategies and methods the researchers used?
- Identify DNA binding sites for transcription factors;
- Map DNA methylation sites;
- Identify sites of histone modification;
- Map sites where DNase I can cleave DNA.
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What result of the ENCODE project was very surprising?
What results underscore the complexity and precision of gene regulation?
Why do the results of the ENCODE project lead to a better understanding of human diseases?
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