Trithorax

5 important questions on Trithorax

Trithorax are a heterogenous group of proteins that match

PcG counterparts



TrxG have a widespread role in

Transcription activation

What are the key players in the TrxG complex

SWI/SNF complex and COMPASS family
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A group of TrxG complexes is associated with histone-modifying activities including histone acetylation and methylation thereby counteracting the

PcG repressive marks

Trithorax response elements are

DNA regulatory elements that recruit TrxG proteins to chromatin therefore, it targets TrxG complexes and therefore it drives the epigenetic inheritance of active chromatin state throughout development

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