Microbioata in health and disease - Microbial components influencing host physiology - Microbial surface molecules
3 important questions on Microbioata in health and disease - Microbial components influencing host physiology - Microbial surface molecules
What are the carataristics of a gram positive bacteria?
cytoplasmic and an outer membrane wih a cell wall and periplasm in between.
Don't contain LTAs but have LPS (lipopolysacharides) . Concists of lipid A (ancher) with and)-specific polysacharide chain. This chain is highly variable.
LPS are considerd toxic for humans (inflamatory response to break down-=> lipid A)
What are other molecues found on the cell envelope?
Flagella
fimbriae - > pathogenic bacteria
pili (longer than fimbriae)
What are contingency genes?
Enable the cell to adhere during infection via fimbriae whale these molecules are absent once infaded. Contingency genes are genes with a gigher mutation rate compared to other genes and allow adaptions of bacterialpopulations to environment)
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