Deficiencies of Vasopressin secretion and action - Diabetes Insipidus - Pathophysiology

5 important questions on Deficiencies of Vasopressin secretion and action - Diabetes Insipidus - Pathophysiology

At which secretion percentage of AVP does the urine output start to rise symptomaticly?

At 85-80%

What happens with the osmolarity of the body fluids when secretion of AVP falls below 85%?

The plasma osmolarity increase slightly.

Why is it difficult to diagnose DI with a cause in the pituitary?

Because the laboratory signs of dehydration do not occur immediately after the disease's onset. Rather symptoms arise from a defect in the thirst mechanism or inadequate fluid intake.
  • Higher grades + faster learning
  • Never study anything twice
  • 100% sure, 100% understanding
Discover Study Smart

Does the osmolaric threshold in somebody with dipsogenic polydisipia lie above or below the threshold of AVP?

Below the threshold of AVP. Therefore somebody feels the urge to drink before the osmolaric capacity of the renal tubes is exceeded. This leads to dilution of body fluids.

How do patients with iatrogenic polydipsia or psychogenic polydipsia react to fluid restriction compared to dipsogenic polydipsia?

They react the same to fluid restriction, in all 3 conditions their excessive fluid intake ceases and thereby increase the threshold of thirst.

The question on the page originate from the summary of the following study material:

  • A unique study and practice tool
  • Never study anything twice again
  • Get the grades you hope for
  • 100% sure, 100% understanding
Remember faster, study better. Scientifically proven.
Trustpilot Logo