Disorders of Anterior Pituitary and Hypothalamus - Hypothalamic, Pituitary, and other sellar masses - Evaluation

5 important questions on Disorders of Anterior Pituitary and Hypothalamus - Hypothalamic, Pituitary, and other sellar masses - Evaluation

Why do pituitary adenomas usually expend in suprasellar direction?

This is because the dorsal part of the sella presents the least resistance to soft tissue.

Which structures can be impacted by sellar mass lesions?

  • pituitary
  • optic chiasma
  • frontal lobe
  • hypothalamus
  • cavernous sinus
  • brain

Which substance allows precise visualisation of the pituitary and the hypothalamus?

Gandolinium
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What are the major functioning pituitary adenomas?

  • Acromegaly (GH)
  • Prolactinoma (PRL)
  • Cushing's Syndrome

Which steps are taken when an pituitary adenoma is suspected following a MRI-scan?

  1. Prolactine levels
  2. IGF-1 levels
  3. urinary free cortisol
  4. FSH and LH levels
  5. Thyroid function

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