Thrombotic risks during pregnancy

3 important questions on Thrombotic risks during pregnancy

How do you treat pregnant women with a VTE in the history?

During pregnancy and after pregnancy the risk of a recurrent thrombosis is higher. You need to give the patient prophylaxis:
  • Provoked: only prophylaxis postpartum
  • unprovoked: start of pregnancy and postpartum prophylaxis

Never give prophylaxis before birth, because there is a high risk of major bleeding.

In what period of the pregnancy is the chance on a VTE the highest for the mother?

Postpartum and the 6 weeks after that, due to immobilization. Give LMWH as prophylaxis.

Why can't you give vitamin K antagonists or DOAC to a pregnant women with a risk of VTE?

Vitamin K antagonists are teratogneitc in the 6-12 weeks in pregnancy. DOAC is not much know off.

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