L7 pharmacology of the autonomous nervous system

4 important questions on L7 pharmacology of the autonomous nervous system

Anatomy of a typical neuron

Neurons or nerve cells
  • receive stimuli and transmit action potentials
  • organization
    • cell body or soma
    • dendrites: input
    • axons: output


neuroglia or glial cells
  • support and protect neurons

Types of neurons: functional classification

  • Sensory or afferent: action potentials towards CNS
  • motor or efferent: action potentials away from CNS
  • interneurons or association neurons: within CNS from one neuron to another

Neurotransmitters; sympathetic postganglionic neuron = -->

  • Release norepinephrine (noradrenaline)
  • maybe excitatory or inhibitory depending on the receptor subtype and the cell type
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Neurotransmitters; parasympathetic postganglionic neuron

  • Release Ach (acetylcholine)
  • usually on muscarinic (GPCR) receptors, effect is usually excitatory

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