Assingments

12 important questions on Assingments

Person-years lived between ages x and x+1 =

(number surviving to age x + number surviving to age x+1) / 2 * n

n= length of time interval

Life Expectancy (LE) VS Years of Life Lost (YLL)

Life expectancy (LE)
  • measures what is being achieved
  • average expressed for 1 person
  • number of years someone can expect to live


Years of Life Lost (YLL)
  • measures what is being lost
  • is expressed for the whole population
  • number of years of potential life lost if dying before a certain age

Expected and potential years of life lost ((EYLL)(PYLL))

Expected years of life lost (EYLL)
  • uses population life expectancy at the individual's age of death
  • problem 1 = different countries may have different life expectancies
  • changes in mortality change life expectancy
  • alternative: reference is to an 'ideal' life expectancy


Potential Years of Life Lost (PYLL)
  • uses fixed age, typically 75
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Survival curve: split by health

Life expectancy: area under the survival curve


health expectancy: area representing good health

Can we make one single measure that takes severity into account? (opname van ernst)

Yes:

health-adjusted life expectancy:

healthy years + part of unhealthy years  (part = weighted with a 'disability weight')

(DALY) Disability-adjusted life-years

The number of healthy years of life lost due to premature death and disability


health gap measure that includes morbidity

Years of life lost berekenen

Years of life lost (YLL) = N x L


N = Number of deaths
L = life expectancy (in standard liftable) at age of death (years)

What is the essential data to calculate DALYs

  • General
    • demographic data (population numbers by age and sex)
  • Years of life lost (YLL)
    • epidemiological data on disease-specific mortality by age (and sex)
    • age-specific life expectancy
  • years lived with disability (YLD)
    • epidemiological data on prevalence of disease (or: incidence and duration) by age (and sex)
    • health status valuations (disability weights)

Why would you measure health and disease?

To inform policy makers on:
  • population health
  • trends
  • differences between groups

Summary measures of population health (SMPH)

Combine these aspects of health into 1 measure

there are many aspects of health:
  • mortality
  • morbidity
  • quality of life
  • disability
  • autonomy
  • participation in society...

History of Global Burden of Disease (GBD); 3 gebeurtenissen

  • World bank report (1993)
  • expanded in the full publication on the fist GBD study (1990 (Murray and Lopez 1996))
    • assessment of mortality and disability from disease
  • first global burden of disease project
    • new analysis
    • development of the DALY

Three major objectives for global burden of disease (GBD)

  1. Inclusion of non-fatal health outcomes
  2. independent, objective evaluations
  3. measure comparable to that used in cost-effectiveness (QALY)

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