2nd + 3rd trimester & birth

34 important questions on 2nd + 3rd trimester & birth

What happens during 1st, 2nd and 3rd trimester?

- 1st trimester: embryogenesis & fetal development (organ systems emerge)
- 2nd trimester: organ development (fetus appears as human)
- 3rd trimester: rapid growth, all organs are functioning.

What is the difference between development and differentiation during prenatal development?

- Development occurs by gradual changes in anatomy and physiology
- Differentiation happens by changes in gene expression

What is the difference between gestational age and fertilization age?

- Gestational age: age counted from the last menses
- Fertilization age: age counted from fertilization
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Embryological features are very much alike across the whole animal kingdom. When do the human features appear development?

At around 3 months after fertilization

What is vernix caseosa, and what is its function?

- A waxy white substance that covers the skin of a newborn baby
- It has a role in skin hydration and pH regulation (only in the first days after being born)

What are two differences for the abdominal organs of the mother?

  • There is increased pressure on the bladder
  • The stomach and intestines have less space

What are the blood vessels of the umbilical cord?

Two arteries and one vein

What is the function of the vein of the umbilical cord?

It supplies the fetus with oxygen-rich and nutrient-rich blood.

What are 6 placental hormones that play a major role in pregnancy?

  • Human chorionic gonadotropin (hCG)
  • Human placental lactogen (hPL)
  • Placental prolactin
  • Relaxin
  • Progesterone
  • Estrogens

What is the function of hCG?

Maintenance of corpus luteum and progesterone level

What is the function of placental prolactin?

Preparation of milk production

What is the function of relaxin?

Relaxin increases the flexibility of the pubic symphesis, which allows the pelvis to tilt during birth.

What is the function of progesterone and estrogens?

They are needed for the normal course of pregancy

What is a thing progesterone does during pregnancy?

It inhibits contractions of the uterine wall.

What are the three main factors that oppose progesterone, and thus play a role in labour?

  • A rising estrogen concentration, which makes the uterine wall more susceptible to oxytocin
  • Oxytocin concentration rises
  • Prostaglandin production, which stimulates oxytocin production and fetal growth.

How is true labor induced?

By
  • Rising levels of estrogens, relaxin, and oxytocin, and
  • Fetal growth, and
  • Dropping levels of progesterone

What are the four stages of true labor?

1. Dilation: positioning of the fetus and dilation of the cervix (most elaborate stage)
2. Expulsion: the head moves out
3. Child birth: the child is completely outside the womb
4. Afterbirth: removal of the placenta

What is the 'transition' in the dilation stage?

The final 2 cm of dilation, which are the heaviest. With full enclosure, the urge for contactions start. In this phase, the 'water break' takes place.

What three things happen during afterbirth?

  • Exogenous tissue is completely ejected
  • Decidua layer from the endometrium is also expelled
  • Blood loss because of uterine contractions

How long does the 'afterbirth stage' last?

With assistence, around 5 minutes.

What helps inducing the afterbirth?

Immediate breast feed, which gives an oxytocin boost. If there is no afterbirth induced, a shot of oxytocin can be given.

What kind of system is used to check whether a baby is okay or not?

The APGAR test:
Activity (muscle tone)
Pulse
Grimace
Appearance
Respiration

How is the first feces of the baby called, and what does it consist of?

Meconium, consists of amniotic fluid swallowed during pregnancy ('trains' the digestive tract), and also gall and blood of the child

How is the first breast milk called, and what does it consist of?

It contains mainly proteins, and it is also rich in antibodies that fight infection until the baby's immune system functions properly.

Why are breast milk alternatives not as good as real breast milk?

The alternatives lack lysozymes.

Why can stress prolong or postpone delivery?

Because adrenaline prevents oxytocin release.

What are two examples of non-vertex presentations?

  • Breech presentation: not ideal, but can be born normally
  • Transverse lie (shoulder presentation): assistance is needed.

What are three possible reasons why the delivery cannot proceed normally?

  • Expulsion is not continuing
  • Fetal oxygen levels are low
  • Pressure of contractions cannot be given for a long time (medical reasons)

What is a risk of a vacuum-assisted delivery?

There is a risk for hemorrhage (head trauma) of the child

What are the risks for the mother after a Caesarean section?

  • Maternal obesity
  • Pregnancy complications
  • Embolies
  • Blood loss
  • Damage to organs
  • Risks for upcoming pregnancies

What is a risk for the child after Caesarean section?

There is no microbiota transfer between mother and child

What things can be done to extend the pregnancy when the mother gets contractions early on in pregnancy?

  • Complete rest
  • Corticosteroids (to fasten lung maturity)
  • Labor inhibitors, block muscle contractions

What is respiratory distress syndrome?

A syndrome in which a premature child
  • has inefficient gas exchange in the lungs
  • needs to much energy for respiration
  • does not produce a sufficient amount of surfactant (causes inflammation and skar tissue)

The development of which part of the brain is disrupted when a child is born premature?

The development of the cerebral cortex (the brain is not ready yet)

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