Common lymphoid progenitor - Lympocytes - T-cells

5 important questions on Common lymphoid progenitor - Lympocytes - T-cells

What is inside of the cytolytic granules in CD8 cytotoxic T cells and Lymphokine activated killer cells?

- Perforin: punches holes in the cell-membrane of target cells
- Granulysin: enters through these holes and induces apoptosis

What is the development of thymocytes accompanied by?

Changes in cell surface molecules

What are the different types of T-cell receptors?

1. Alphabeta
2. gammadelta
3. NK T cells (unique alphabeta)
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What does an alpha beta TcR consist of?

variable (V) amino terminal and a constant (C) region

Which cytokines are produced in the Th1 CD4+ T cell?

-IFNy
- IL-12

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