Clinical immunology - Cancer

5 important questions on Clinical immunology - Cancer

What is the effect of VEGF on DCs?

Tumor infiltration and differentiation

What is the effect of gangliosides on DCs?

Inhibition of DC migration

What is the effect of IL-10 on DCs?

Differentiation, CD80/CD86/CD40 expression, IL-12 production
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What is the effect of PGE2 on DCs?

Downregulation of MHC Class I and II

What is the ABCDE of melanoma?

Assymetry
Border irregularity
Colour variation
Diameter
Evolving

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