Antibodies - IgA - IgE

4 important questions on Antibodies - IgA - IgE

Which kind of IgE receptors are there?

High affinity receptor: FceRI
Low affinity receptor: FceRII

Where can you find FceRI receptors and how do they differ?

FceRI (abyy) on mast cells --> degranulation
FceRI (ayy) on APCs

Where can you find FceRII receptors and what is their function?

B cells (in soluble form), they regulate IgE synthesis
Eosinophils, monocytes/macrophages, function unknown
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Is IgE transported across the epithelium or placenta?

No

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