The development of B lymphocytes - Induction of immune responses (I)
4 important questions on The development of B lymphocytes - Induction of immune responses (I)
What are the thymus dependent responses?
What is the thymus independent responses?
Where do naive B cells find their antigen?
They keep intact Ag on their surface by which B cells can be activated.
Complement receptors bind to complement coated Ag.
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How do you get different isotypes?
Naive B cells (before they have bound Ag) express IgM and IgD on their membrane. These are the only isotypes that can be simultaneously be produced by B cells. After activation of naive B cells IgM is produced first.
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