Immune induced alterations in plasticity-related molecular and cellular processes - Neurotrophins - BDNF

3 important questions on Immune induced alterations in plasticity-related molecular and cellular processes - Neurotrophins - BDNF

Which cells do express BDNF and its receptor Trk-B?

  • neurons
  • microglia
  • astrocytes

What is the anti-inflammatory effect of BDNF on microglia and how does it work?

BDNF can induce sustained elevation of intracellular Ca2+ (Mizoguchi et al., 2009)

What are the effects of BDNF on microglia?

  • autocrine proliferation and survival
  • influencing neuronal functioning

The question on the page originate from the summary of the following study material:

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