Activation of B Cells and Antibody Production

4 important questions on Activation of B Cells and Antibody Production

How do B cells recognize antigens in body fluids?

Recognition occurs through B-CELL RECEPTORS (BCRS), which are:
  • Membrane-bound forms of antibodies
  • Specific for free-floating antigens
  • Vital for initiating immune response

What is the role of helper T cells in B cell activation?

They provide essential signals by:
  1. Activating CD4+ helper T cells
  2. Releasing cytokines
  3. Fully activating the B cell

What happens to B cells once they are fully activated?

Fully activated B cells:
  • Differentiate into PLASMA CELLS
  • Produce large quantities of ANTIBODIES
  • Specifically target the pathogen
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How do antibodies function once produced by plasma cells?

Antibodies serve several functions by:
  1. Binding to pathogens or toxins
  2. Neutralizing threats
  3. Marking for destruction by immune cells (e.g., phagocytes, natural killer cells)

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