Summary: Immunology

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  • Lecture 1

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  • How do pathogens come into the body? Why via these tissues?

    Via mucosal tissues because these tissues are very permeable.
  • What are examples of mucosal tissues?

    • Respiratory tract
    • Urogenital tract
    • Gastrointestinal tract
  • What are two different classifications of pathogens?

    • Intracellular
    • Extracellular
  • What immune cells belong to the innate immune system?

    • Granulocytes (short life cycle)
    • Macrophage
    • Neutrophils
    • NK cells
    • Complement
  • What is the difference between granulocytes and macrophages?

    Granulocytes kill bacteria and macrophages 'eat' big particles.
  • What does CD mean in CD4 and CD8?

    Cluster of deviation
  • When do you speak of a disturbed immune system?

    • Autoimmune diseases (against 'self')
    • Allergies

    These are both immune responses against harmless things.
  • What is so special about the immune system?

    The immune system is a balance between activation and inactivation (immunity vs tolerance).
  • How can you artificially induce immune responses?

    • Vaccination
    • Anti-tumor therapy
  • What are the three levels of protection?

    1. Barriers: skin, mucous, membranes, chemicals
    2. Innate immune response: immediate response, fast, not specific
    3. Adaptive immune response: slow to be activated, very specific

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