Autoimmunity
7 important questions on Autoimmunity
Why are tolerance and autoimmunity so closely related?
What is the difference between auto-inflammatory and autoimmunity?
What is thought to be the reason of autoimmunity?
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Can body take any precautions while immune system is developing such that these autoreactive cells are not produced?
How can a B-cell damage the tissue?
2. When the B cell is activated by a T-cell specific for the self-peptide the B cell differentiate into plasma cells
3. These cells secrete a large amount of self-antigen specific antibodies.
4. At the site of the injury, the self-antigen specific antibodies initiate an inflammatory response which cause more cell injuries.
5. More B cells bind to the antigens, and this amplified the cycles and the tissue damage.
What is a clue that genetics plays a role in autoimmune diseases?
What are immunologically privileged sites and some examples in the body?
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