Defence against bacteria
8 important questions on Defence against bacteria
Which type of responses are important in elimination of bacteria?
- Type 1 intracellular bacteria
- Type 3 extracellular bacteria
What are the most important cells in the type 1 response?
- group 1 ILCs
- Th1 cells
- opsonizing IgG antibodies
- Macrophages.
What are the most important cells in the type 3 response?
- Group 3 ILCs
- Th17 cells,
- opsonizing IgG antibodies
- Neutrophils.
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What happens when the body encounters the antigen for a second time?
- There is a shorter lag-period
- There are high levels of antibody and primarily IgG
- Higher affinity of the antibody to the specific antigen
What does the bacteria do to establish an infection?
- Adhere to the epithelial surface and colonise
- Penetrate to replicate in the tissue when physical barriers are broken
What does the bacteria encounter first when physical bariers are breached?
Which PRR are there to recognize the bacteria?
- C-type lectin family recognize the microbial sugars
- Scavenger receptors recognize the cell wall and lipids.
- NOD-like receptors recognize the intracellular peptidoglycans.
- Multiple toll-like receptors.
- fMet-Leu-Phe (fMLF) receptor
What are the three main function of an inflammation reaction?
- Destroy invading microbe
- Induce local blood clotting to reduce the spread of infection through the bloodstream
- Repair injured tissue
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