Defence against bacteria - Innate immunity - physical en chemical
7 important questions on Defence against bacteria - Innate immunity - physical en chemical
What are the physical and chemical barriers to a viral infection?
- Type I IFNs (IFNα and IFNβ)
- Microbicidal peptides.
What is the function of TNFa?
- Stimulates expression of adhesion molecules
- Attracts monocytes and neutrophils
- Stimulate endothelial cells to express proteins that trigger blood clotting in the local small vessels.
What is the function of IFNb?
- Induces the cell to make IFN-a
- Amplifies the interferon response
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Which functions do IFN-a and IFNb have?
- Induce resistance to viral replication.
- Increase MHC class I expression and antigen presentation in all cells.
- Activate dendritic cells and macrophages.
- Activate NK cells to kill virus-infected cells.
- Induce chemokines to recruit lymphocytes.
Which cells produce Type 1 interferons (IFNa and IFN-b)?
What is the difference between type II and Type I interferons?
Type II interferon (IFN-gamma) is mainly produced by T cells and natural killer cells. It plays a key role in regulating the immune response, particularly in activating macrophages and enhancing antigen presentation.
What can the role of the complement system be?
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