Basic immunology

9 important questions on Basic immunology

What did Emil Behring & Paul Ehrlich discover? And what was this the basis for?

Antibodies, this was the basis for acquired immunity.

What produces the complement proteins?

Macrophages & hepatocytes

What are the functions of the complement proteins?

  • Recruitment of inflammatory cells
  • Tags surface of pathogens
  • Cytolysis pathogens
  • Removal ab-ag complexes
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What happens if there is a T-cell deficiency?

Failure to control a pathogen after infection.

What happens if there is an antibody deficiency?

More susceptible for infection but normally cleared.

What is the function of IgA?

Present in body secretions (mucosa)

What is the function of IgG?

'Late' response, crosses the placenta

What is the function of IgM?

'Early' response, good agglutinator

What is the function of IgD?

On the surface of B cells but function unclear

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