Motor control - Corticobulbospinal terminations

10 important questions on Motor control - Corticobulbospinal terminations

What is bilateral innervation?

2nd motor neurons that receive innervation from 1st motor neurons on both sides

--> less vulnerable to lesions

Where do the axons that innervate the bilateral areas cross over?

In the brainstem

Which areas are bilaterally innervated?

- Trigeminal motor nucleus (mastication)
- Dorsal facial motor nucleus (mimical musculature upper half face)
- Ambiguous nucleus (swallowing)
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Which areas do not receive information from the primary motor cortex?

Oculomotor nuclei (movement eyes) and visceromotor nuclei in brainstem. This are both smooth muscles

What is the difference between the crossed and uncrossed corticospinal tract?


Crossed - crossed over to the other side
Uncrossed - not crossed over and projects bilaterally

What are the secondary motor control pathways?

- rubro-spinal tract
- reticulo-spinal tract
- vestibulo-spinal tract
- tecto-spinal tract

--> all influence through interneurons, never directly to motor neurons

What is the rubro-spinal tract (secondary motor control pathway)?

- Axons that originate from nerves in the red nucleus.
- Cross over
- The red nucleus receives input from the cerebellum and (motor) cortex.
- This tract plays an important role in motor learning.
- It projects mainly to cervical intumescence flexor motorneurons (held responsible for partly recovery after lesions).
- Eventually, terminates in ventral root (anterior grey column)

Evolution: more corticospinal and less rubrospinal

What is the reticulo-spinal tract (2nd motor control pathway)?


- axons originate from reticular formation in pons or medulla
- cross over
- regulation of postural reflexes
- control of tone of muscles in relation to stance
- control of general excitability of motor neuron pools
  • all muscles need a little bit of stimulation before they can be activated by the corticospinal tract
- two tracts
  • Medial reticulospinal tract
    • increases activity of reflexes (stimulates excitatory neurons)
  • Lateral reticulospinal tract
    • decreases activity of reflexes (stimulates inhibitory neurons)

- terminate in ventral horn

What is the vestibulo-spinal tract (equilibrium, 2nd motor control pathway)?

- Originate from vestibular nuclei in pons and medulla oblongata
- Descend uncrossed
- Synapse with neurons in ventral horn


- Information about the head position -> maintenance of equilibrium
- Coordination of eye and neck/trunk movements
  • Vestibulo-collic reflex stabilizes head through neck movements
  • Vestibulo-spinal refect stabilizes body through postural movements

What is the tecto-spinal tract (2nd motor control pathway)?

- Originates from brainstem (superior colliculus)
- Descend crossed
- Terminates in ventral horn
- Visual (and auditory) information to neck and upper trunk; coordination of the eye and neck/trunk movements

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