Aldehydes and Ketones - What Are Hemiacetals and Acetals?
8 important questions on Aldehydes and Ketones - What Are Hemiacetals and Acetals?
What is a hemiacetal?
What type of molecules can form a stable hemiacetal?
Under what conditions are acetals usually synthesized?
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How do you determine the reactants used to synthesize a hemiacetal or an acetal?
2. Remove both C-O bonds. Add a proton to both oxygen atoms. Convert the previous identified carbonyl-carbon to a carbonyl group.
Why are acetals used to protect the carbonyl groups of aldehydes and ketones?
Why can a Grignard reagent not be used in the reaction between benzaldehyde and 4-Bromobutanal to form 5-hydroxy-5phenylpentanal?
How can the carbonyl group of 4-Bromobutanal be protected against reacting with the Grignard reagent?
How will the cyclic acetal then react with the benzaldehyde?
The formed magnesium alkoxide will be treated with aqueous acid resulting in a hydrolysis and recovery of the carbonyl group.
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