Aldehydes and Ketones - How Do Aldehydes and Ketones React with Ammonia and Amines?

4 important questions on Aldehydes and Ketones - How Do Aldehydes and Ketones React with Ammonia and Amines?

How are Imines catalyzed?

The reaction of Ammonia, primary aliphatic amines (RNH2), and primary aromatic amines (ArNH2) react with the carbonyl group of ketones and aldehydes in the presence of an acid catalyst to Imines or Shiff bases. This reaction is reversible.

What are the steps in Imine formation from an Aldehyde or Ketone?

1. Reaction of an electrophile and a nucleophile to form a new bond.
2. Addition of a proton to the -OH group.
3. Proton and water removal to form the carbon-nitrogen double bond.

What is a important Imine formation reaction in the human body?

The formation of Rhodopsin from retinal and the protein opsin.
  • Higher grades + faster learning
  • Never study anything twice
  • 100% sure, 100% understanding
Discover Study Smart

What is reductive amination?

It is the formation of an Imine from a ketone or aldehyde, which is then followed by the reduction of the Imine to form an amine.

The question on the page originate from the summary of the following study material:

  • A unique study and practice tool
  • Never study anything twice again
  • Get the grades you hope for
  • 100% sure, 100% understanding
Remember faster, study better. Scientifically proven.
Trustpilot Logo