Bacterial breach (2nd layer)
3 important questions on Bacterial breach (2nd layer)
What is the second layer of defense?
Rapid detection and killing of bacteria which penetrated the intestinal tissue.
In what pathways are bacteria capable of triggering pro-inflammatory responses, NF-kB (4)?
1: Surface recognition (TLRs), endocytosis of PAMPs, protein toxins (pathogens/commensals;
2: Adherence and secretion tocins (C. difficile, B. fragilis);
3: Injection of effectors by type III and IV secretory systems (needles) (EPEC, EHEC, H. pylori);
4: Invasion (Shigella, Salmonella)
How are phagocytes recruited to a breach?
Via a chemokine gradient (CCL20) to the breach;
Via diapedesis of the capillary wall.
The question on the page originate from the summary of the following study material:
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding
