Membrane transporter

4 important questions on Membrane transporter

What particlues can go through membrane by passive diffusion?

Hydrophobic particules

What is a transporter? Name 3 different ones

Transporter is activated by the binding of a molecule and a conformation change occurs
  • Uniporter: transports 1 molecule
  • Symporter: transports 2 molecule same direction
  • Antiporter: transports 2 molecule by exchanging

Which are ATP powered pumps?

  • Natrium kalium pump
  • Calcium pump
  • ATPases
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What is a ABC transporter?

Is for hydrophobic (lipids) and amphipathic molecules (molecules you don't want to have in the body)
  • are not phosphorylated, but only hydrolyse ATP into 2 ATP-binding domain
  • outward transport
  • ABCB1 present in normal cells (endothielicum, epithelium and stam cells)

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