Skin and biomaterial infection - Antibiotics

6 important questions on Skin and biomaterial infection - Antibiotics

What is the target of Penicillins, ampicillin, cephalosporins, bactracin, vancomycin?

Cell wall synthesis

What is the target of streptomycin, cholaroamphenicol, erythromycin, tetracyclins, gentamicin, kanamycin?

Protein synthesis, block ribosome (translation)

What is the target of sulfonamide, trimethoprim?

Synthesis esseential metabolies
  • enzymes metabolic pathways
  • folic acids
  • Higher grades + faster learning
  • Never study anything twice
  • 100% sure, 100% understanding
Discover Study Smart

What is the target of Quinolones, Rifampin?

  • DNA synthesis (replication)
  • RNA synthesis (transcription)

Active vs Passive antibiotic resistance

Active resistance
  • Enzymes digesting or modifying antibiotics (ß-lactamase, ESBLs Carbapenemases, aminoglycosidase)
  • Active excretion of antibiotic, membrane protein pumps


Passive resistance
  • Change in target so antibiotic will not bind
    • Alternative PBP’s → MRSA
    • Point mutations

Explain Horizontal gene transfer of resistance genes

  1. Conjugative plasmids: sex pili
  2. (Conjugative) transposons: transposase, “jumping genes”
  3. Natural competence: uptake foreign naked DNA
  4. Bacteriophages

The question on the page originate from the summary of the following study material:

  • A unique study and practice tool
  • Never study anything twice again
  • Get the grades you hope for
  • 100% sure, 100% understanding
Remember faster, study better. Scientifically proven.
Trustpilot Logo