Brain substrates of episodic and semantic memory - subcortical structures involved
3 important questions on Brain substrates of episodic and semantic memory - subcortical structures involved
what function is ascribed to the diencephalon in episodic and semantic memory?
it may help guide consolidation. - but not sure
may be responsible for interaction between frontal cortex and hippocampus during memory storage and consolidation -> damage disrupts interaction
what is korsakoff and what memory issues does it cause?
deficiency in thiamine because of chronic alcohol abuse -> damages mammilary bodies and mediodorsal nucleus of the thalamus in diencephalon.
they get anterograde amnesia and time-graded (ribot gradient) reterograde amnesia
they often show confabulation; makeing up stories of what they did that they actually believe
what role of basal forebrain in episodic nd semantic memory?
may help determine what the hippocampus stores.
because of aneurisms in anin coming artery often brain damage here -> amnesia like in medial temporal lobes, just like korsakoff's.
some neurons from basal forebr send gaba nd acetylcholine to hippocampus and affect neuroplasticity here, which helps determine how likely hippocampus is to store info.
one theory: basal forebrain tells hippocampus when to store info and when not
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