Cortical Dementia
15 important questions on Cortical Dementia
What are the diagnostic criteria for definite FTD-bv?
- Histopathological evidence and/or pathogenix mutation.
What is found in NPA in FTD?
- Visuoconstruction: perseveration.
- Memory is relatively intact.
What brain areas are affected in FTD?
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What are the diagnostic criteria for PPA?
- Principle cause of impaired ADL.
- Aphasia most prominent deficit at the onset and initial phase.
What are exclusion criteria for PPA?
- Cognitive disturbance better accounted for by psychiatric diagnosis.
- Prominent initial episodic or visual memory and visuoperceptual impairment.
- Prominent initial behavioral disturbance.
What are the three subtypes of PPA?
- PPA semantic dementia
- PPa logopenic progressive aphasia
What are the diagnostic criteria o PPA non-fluent?
Two of: Impaired comprehension syntactically complex sentences, spared single-word comprehension, or spared object knowledge.
What are the diagnostic criteria for PPA semantic dementia?
Three of: impaired object knowledge, surface dyslexia/dysgraphia, spared repetition, or spared speech production.
What are the diagnostic criteria for PPA logopenic progressive aphasia?
Three of: phonological speech errors, spared single-word comprehension and object knowledge, spared motor speech, and absence of frank agrammatism.
Which brain areas are affected in PPA?
SD: anterior temporal
LPA: left posterior perusylvian or parietal
What are the core features of Lewy Bodies dementia?
- Recurrent visual hallucinations
- REM sleep behavior disorder
- Spontaneous features of parkinsonism
What are supportive features of Lewy Bodies dementia?
- Repeated falls, postural instability and syncope
- Transient, unexplained loss of consiousness
- Severe autonomic dysfunction
- Hallucinations other modalities
- Systematized delusions
- Depression, apathy, anxiety
What are indicative biomarkers for Lewy Bodies dementia?
- Abnormal uptake in myocardial scintigraphy
- REM sleep confirmation Polysomnographic
What are supportive biomarkers for Lewy Bodies dementia?
- SPECT: parieto-occipital hypoperfusion
- Slow-wave EEG with period fluctuations
What is found in NPA in Lewy Bodies dementia?
- Attention
- Executive functioning: mental inflexibility, attention
- Memory, later stages: variable learning curves
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