Genetic variation end human diseases - how do mutation arise?
3 important questions on Genetic variation end human diseases - how do mutation arise?
Why are de novo mutations needed?
- Crucial for evolution
- most of the mutations are neutral
- the others cause disoders or are benifical
Why do gentic disease have a constant prevalence (affected people in population)?
- Novel variants in individual genomes
- reproduction creates genetic variantion
- genetic variantion drives adaptation and evolution
- and may cause genetic diseases
Single nucleotide polymorphisms (SNP)?
Is the variant of the allel, so 3 different options per allel.
the most common ones is de SNP
the most common ones is de SNP
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