Functionall elements in the genome - RNA types
3 important questions on Functionall elements in the genome - RNA types
Short interfering RNA (siRNA)?
- Often derived form pseudogenes.
- involved in gene regulation in somatic cells and types of transposon.
- >10,000 siRNA derived form pseudogene
PiRNA (piwi-interacting RNA)
- function in embryonic development,
- maintenance of germline DNA integrity,
- silencing of transposon transcription,
- suppressionof translation,
- formation of heterochromatin,
- epigenetic regulation of sex determination
- >15,000 piRNA inhibt retrotransposon acticity in germ line
Non-coding RNA (ncRNA)?
- function as modulators of epigenetics through chromatin remodelling
- or regulate gene expression at transcriptional
- or post-transcriptional level.
- >3,300
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