Antigen-presentation, B- and T-cell effector mechanisms; The basis of immunological tolerance; Autoimmunity in general; B cell and T cell autoreactivity
12 important questions on Antigen-presentation, B- and T-cell effector mechanisms; The basis of immunological tolerance; Autoimmunity in general; B cell and T cell autoreactivity
What is the prevalence and incidence of Diabetes mellitus in the NL?
What is the prevalence and incidence of RA in NL?
How are T cell receptors generated?
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On what is the classifiaction of autoimmune diseases based?
What types of Classification of autoimmune diseases are there?
The entire adaptive immune system is involved in autoimmune diseases. Name the role of Tcells, Bcells and antibodies for systemic lupus ertthematosus.
What is the definition of immunological tolerance?
The chance of developing tolerance depends on certain aspects of the antigen. Which?
Explain how the central tolerance of Bcells works.
Name 4 characteristics of CD4+T suppressor cells
Name the 3 mechanisms to suppress or turn-off autoreactive lymphocytes. How do they do it, and with which cells.
Name the 9 mechanisms that contribute to immunological self-tolerance.
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