Nutrition and mental health
22 important questions on Nutrition and mental health
Of which 9 symptom do you have to have at least 5 symptoms for >2 weeks to be diagnosed with major depressive disorder?
2. Lack of interest
3. Sleep problems
4. Appetite/weight changes
5. Low energy
6. Concentration problems
7. Psychomotor retardation or agitation
8. Guilt or worthlessness
9. Suicidal ideation
The first 2: at least one of these 2 has to be present
What is the % prevalence of major depressive disorder in lifetime?
Name 5 types of factors/mechanisms that can contribute to developing major depressive disorder
psychosocial factors (personality, life events)
behavioral factors (smoking, alcohol, nutrition (?))
somatic health factors (CVD, diabetes, pain)
Biological factors (inflammation, cortisol)
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Name 4 different nutrients that has been studied to have a link with depression
- zinc
- folate
- vitamin D
Name 2 examples of foods that have been studied in relationship with depression
- vegetables
Name 3 limitations from an ecological study that is done between 7 countries, fish intake and prevalence of depression.
- you dont know if the people with lower fish intake have higher prevalence of depression
- you cannot say anything about causation.
What 4 things are said about omega-3 fatty acids in relation to depression?
- there is a small to moderate positive effect of omega-3 PUFAs on depression compared to placebo
- Lower fish intake and omega-3 intake is related to depression
- lower blood levels of omega-3 PUFAs is related to depsreeion
What is said about folate and depression?
What is said about zinc and magnesium in relation to depression?
What is said about vitamin D supplementation and depression?
What does the approach 'a priori' mean with dietary data?
What does the approach 'a posteriori' mean with dietary data?
What is said about the quality of the diet in relation to depression?
when you have low quality diet (lots of sugar, fats) some study found that it did not result in higher depression risk, some found there might be an effect of low quality diet on depression risk.
What is the research question of MooDFOOD?
What where the 3 inclusion criteria of the MooDFOOD study?
- BMI 25-40
- depressive symptoms
What where the 3 exclusion cirteria of the MooDFOOD study?
- other psychiatric disorders
- already taking supplements
What where the 2 nutritional interventions int he MooDFOOD study?
- food-related behavioral activation (21 sessions (15 individual, 6 group), focus on healthy dietary habits, emphasizing mediterranean diet) vs no therapy
What was the primary finding of the MooDFOOD study?
What where the 3 secondary findings of the MooDFOOD study?
- F-BA improved two unhealthy eating styles (emotional eating and uncontrolled eating)
- Both interventions had no effect on bodyweight
What is the conclusion in general about nutritional strategies and the prevention of MDD?
What is the difference in the results between observational studies and intervention studies for omega-3 PUFAs and depression?
- intervention studies: small-to-moderate positive effect of omega-3 PUFAs on treatment of depression compared to placebo, especially for clinical depression and EPA
What was the study design the MooDFOOD study used?
its very efficient to do
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