In dept questions - Extra vragen
6 important questions on In dept questions - Extra vragen
What are the 3 most important characteristics of stem cells?
- Not terminally differentiated
- Can divide without a limit
- Upon division, daughter cells either remain a stem cell, or embarks on a course towards terminal differentiation
What are the differences between embryonic stem cells, induced pluripotent stem cells and somatic stem cells?
- Totipotent
- Can form new organism
Embryonic stem cells:
- Pluripotent
- Can form all tissues
- Cannot form an entire new organism
Gastrula and Adult stem cells:
- Multipotent
- Form endo-, meso- and ectoderm
Somatic stem cells:
- Unipotent
- Can form one tissue
Induced pluripotent cells:
- Somatische stamcel gededifferentieerd tot pluripotente stamcel
- door 4 master regulatoire transcriptie factoren tot expressie te brengen
How are stem cell niches in plants and animals alike?
- Somatic stem cells are generally located in a stem cell niche: organizer + stem cells
- Stem cells divide slowly. Differentiating daughter cells divide rapidly before they terminally differentiate: transient amplifying cells
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What is a stem cell niche?
What are transit-amplifying cells?
Dochtercellen die op weg zijn om gedifferentieerde cellen te worden kunnen, meestal onder invloed van een morphogen, erg snel delen.
Deze snel delende dochtercellen zijn de transit-amplifying cells.
Wat doen Paneth cells (secretory cells) in de stam cell niche?
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