Host defense - Auto-immunity [21%] - Glomerulonephritis

11 important questions on Host defense - Auto-immunity [21%] - Glomerulonephritis

What is affected in the kidney with the following data: GRF low, 10g proteinuria, low albumin

Podocytes

Loss of protein in the urine (proteinuria), low serum albumin, and edema

Nephrotic syndrome

What is the pattern of injury called when podocyte receptors of the kidney are attacked

Membranous glomerulopathy
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Which hypersensitivity reaction is it when receptors on podocytes are attacked and cause a complement system activation?

Type II

Low blood pressure, GFR really low, urine sediment has blood (hematuria) and leukocytes (leukocyturia) -> What does this suggest?

Nephritic syndrome

When something breaks down in the glomerulus what is that called?

Nephritic syndrome

When a moonshape is formed near the capsule of Bowman due to an immune cell reaction, what is that pattern of injury called?

Crescentic glomerulonephritis

What type of hypersensitivity reaction causes auto-antibodies against GBM (COL4A3) [anti-GBM-nephritis] {in the lung too, goodpasture's syndrome}

Type II

Proteinuria, edema, arthritis, active sediment, antibodies against DNA: what would you expect

Lupus

For what kidney disease is every fluorescence that you stain for positive?

Lupus nephritis

What two patterns of injury do you get for lupus nephritis

Mesangiocapillary, membranous glomerulonephritis

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