Host defense - Auto-immunity [21%] - Myasthenia gravis
29 important questions on Host defense - Auto-immunity [21%] - Myasthenia gravis
Which hypersensitivity type is tissue specific?
Which hypersensitivity type is mostly cytotoxic?
What percentage of myasthenia gravis is acquired (auto-immune)?
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What is attacked/compromised in myasthenia gravis, what location?
What does MuSK recruit?
What does agrin bind?
Where do antibodies bind in LEMS?
What do patients with antibodies against AChR on their muscles have?
Which type of myasthenia gravis is focussed on the head primarily the eyes and the upper torso? Abbreviation is fine
Which form of MG has predominant muscle weakness of the upper legs, towards cranial progressively
What part of the complement system inflicts damage in cytotoxic mechanism 2 in MG
What two things are lost due to Cytotoxic mechanism 2 in MG?
What is the mechanism called that due to crosslinking receptors are endocytosed, internalized and degraded in the tissue?
What other mechanism is there apart from cytotoxic mechanism 2 and noncytotoxic mechanism to impair transmission from the synapse to the muscle?
What is ascending weakness a clinical clue for?
What type of MG is associated with sweating, dry mouth and erectile dysfunction?
What type of antibodies are VGCC antibodies?
Which mechanisms are used in LEMS
What plays a less important role in LEMS than in MG
Which MG has slurred speech and problems swallowing?
Which type og MG have respiratory crises in 50% of some cases at some point
What antibody is associated with MUSK
Which IgG does not bind complement, and does not activate Fc receptor mediated cytotoxicity?
What IgG can exchange Fab sites with other antibodies and become bispecific at the cost of becoming monovalent binding?
Linking between what two molecules does IgG4 binding to MuSK obstruct?
What type of mechanism is associated with MuSK?
What tumor is associated with LEMS
What type of MG is pemphigus vulgaris close too if you look at its underlying molecular mechanisms? IgG4, direct block, no tumor association and DQ5-DR14 HLA?
Which hypersensitivity type is associated with MG
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