Fat, cholesterol, and atherosclerosis
29 important questions on Fat, cholesterol, and atherosclerosis
How does a myocardial infarct or stroke occur?
What is a prevention of getting a heart attack when you have clogged a artery?
Triglycerides are high in which lipoproteins?
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What happens to the fats in your diet?
What happens to fats in between diets or when you're on a fat free diet?
What is the difference between the LDL and chylomicron protein?
What is forward (cholesterol) transport?
How are atherosclerotic plaques formed?
The macrophages have special receptors for OxLDL. What are these called?
What are metalicmetalproteases (MMPs)?
What can happen to the vessel wall if you have a lot of inflammation (because of an atherosclerotic plaque)? What happens next?
What is the function of HDL particles?
Which lipoprotein is associated with HDL particles?
What happens if you have a mutation in the ApoA1?
Why is it better to look at the ratio LDL/HDL? What is better: high or low ratio?
What are the changes associated with insulin resistance?
- Increased ApoB (LDL will increase)
- Decreased ApoA1 (HDL will decrease)
- Small dense LDL and HDL
- Increased ApoC3 (more chylomicrons)
What is the consequence for your liver of having a high amount of fat in your diet?
What is a better way to predict the chance of getting heart disease than looking at cholesterol levels?
Not 100% of the cholesterol is ingested through the diet. What is done to get to 100%?
What have companies done when they say they can lower cholesterol levels?
What is familial hypercholesterolemia?
How does cholesterol regulate its own synthesis?
What is the mechanism of statins?
You can make different types of FA, except for 2. Which one?
One of the most important enzyme of eicosanoids is?
What is the mechanism of aspirin (and other painkillers)?
What happens if you only block COX2 (since only this one is induced by inflammation)?
There have been some drugs that block COX2. What is the name of these?
What is the mechanism of glucocorticoids?
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