Summary: Metabolic Aspects Of Nutrition
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3 vitaminen
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Which vitamins are antioxidant?
Vit E en C -
Which are h/e- donors/acceptors?
Vit B,C en K -
vitamine E "the fat antioxidant" in vegetable oils
= tocopherols and tocotienoes with biological activity of RRR-a.. Antioxidant (stabilization of cell membranes, regulation of oxidation reaction)
-regulation of gene expression
-intra cellulair 'second messenger' -
Vitamine K "The green leafy vitamin"
-Synthesis of blood-clotting proteins
-bone proteins that regulate blood calcium
-in liver, milk and leavy green vegetables -
Vitamine C "the citrus antioxidant" defiency:
-anemia (small-cell type)
-aTHEROSCLEROTIC Plaques
-poor wound healing -
Vitamine C protects..
-dna oxidation
-protection of proteins from oxidation
-protection of LDL against extracellular -
Function vitamin C
-cofactor: electron donor
-connective tissue function and strength (collagen hydroxylation)
-energy production
-peptide metabolism
-bile acid synthesis
-gene expression -
Folate (B9,B10,B11) "the DNA creator" Defiency
-neural tubedefects
-megaloblastic anemia
-risk for certaincancers
WITHOUT FOLATE, dna strand break and cell division diminishes -> megaloblastic anemia: red blood cells cannot carry oxygen or travel through the capillaries efficiently -
B12 "the blood maker" defiency:
-megaloblastic anemia
-neurological disease
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function: production red blood cells
ONLY ANIMAL FOODS -
Thiamin "the carbo burner"
Defiency:
-beriberi
-muscular weakness
- Wernicke-korsakoff syndrome
sources: whole grain, pork
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