Summary: Microbiology

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Read the summary and the most important questions on Microbiology

  • Virulence Factors (MIC 9)

    This is a preview. There are 15 more flashcards available for chapter 18/01/2019
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  • There is a dynamic equilibrium between host and microbes. What is the off-balance called between host and pathogen?

    Infectious disease.
  • Infection takes place in five steps, give these steps.

    1. Adherence
    2. Invasion
    3. Colonization
    4. Tissue damage/disease
    5. Further exposure
  • What is the function of a capsule?

    A capsule may help with attachment to epithelial cells.
  • What are the virulence factors of salmonella that are used for invasion?

    • Injectosomes
    • Virulence plasmid
  • Invasion can be performed in several ways. What are two possible ways?

    • Zipper mechanism
    • Trigger mechanism
  • What are the virulence factors of salmonella that are used in step 3, colonization and growth?

    • Siderophores
    • Anti-phagocytic proteins induced by oxyR
    • O antigen
    • Vi capsule antigen
  • What is the function of O antigen?

    It inhibits phagocyte killing.
  • What is the function of Vi capsule antigen?

    It inhibits complement binding.
  • What is typical for staphylococcus aureus?

    It produces fibers that will remain around the infection so it cannot spread.
  • What is the advantage of having a capsule?

    Having a capsule prevents phagocytosis by bacteria, so they are harder to 'catch'.

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