Class 6 Practical
10 important questions on Class 6 Practical
What determines whether and how much gene is transcribed?
- Histone-binding
- transcription factors
- promotor region
- DNA-polymerase
- methylation
- repressor/enhancer segments
What determines how much a functional protein is produced by the cell?
- phosphorylation
- stability
- miRNA
- cleavage of signaling peptides
- ubiquination
What is cell-cell signalling for?
- survival
- growt/mitosis
- apoptosis
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Is BMP signalling fast or slow?
What kind of molecules can directly dignal to the nucleus?
How is receptor transduction conducted? (fig 16.13)
- receptor binding
- structural transformation with scaffold
- activation of 2nd messenger
- second messenger cascades to DNA
- altered metabolism and gene expression
What is the main on-off switch in the cell?
What type of receptor is the BMP receptor?
What methods can be used to target/prevent BMP signalling in FOP?
- Smad inhibitors
- allele specific RNAi
What does: 'induction of dimerization' mean?
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