Epithelial-Mesenchymal transition (EMT) - Concept of EMT
3 important questions on Epithelial-Mesenchymal transition (EMT) - Concept of EMT
What are adherens junctions and how are they involved in EMT?
Adherens junctions are in epithelial cells, when they dissolve the cell can move freely around.
EMT is the loss of epithelial characters and aquires mesenchymal features
EMT is the loss of epithelial characters and aquires mesenchymal features
Where and when does EMT occur?
ETM occurs in the development of an embryo at the primitive streak and neural crest
What is the role of EMT in cancer?
Primary epithelial tumor cell becomes an invasive migratory tumor cell
(Fibrosis is also a disease with EMT defect)
(Fibrosis is also a disease with EMT defect)
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