Summary: Neuronglia Development
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Glia development
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What is the role of pericytes in the brain?
We do not know, they are like astrocytes. -
What are the astrocytes subtypes?
- fibrous
- protoplastic
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Where do fibrous astrocytes reside?
In the white matter and express GFAP. -
Which astrocytes are characterized by GFAP?
fibrous astrocytes -
What is the role OPCs in synapses?
They help neurons to form synapses. -
What is the function of NG2 cells?
They can become protoplasmic astrocytes, then oligodendrocytes. So it is a sort of replenisher. -
What is yet unknown in relation to oligodendrocyte markers?
The factors are not super subtype specific because they are mostly related to myelination. -
Where do glia originate?
neuroepithelial cells that line the cerebral ventricles and spinal canal, they make embryonic radial glia, which gives rise to astrocytes and oligodendrocytes.- neuroepithelial cells
- radial glial
- intermediate progenitors
- adult cells
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Where do neural progenitors reside?
Near the ventricles. -
Explain neural tube diversity
SHH, BMP and other factors create unique environment that induces unique gene expression.
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