L10 Chemical senses

5 important questions on L10 Chemical senses

Olfaction is mediated by Type ___ receptors while gustation is by Type ____ receptors.

Olfaction is mediated by Type I receptors while gustation is by Type II receptors.

Which statement(s) is/are false?

1. Olfactory receptor cells are neurons that line the upper portion of the nasal cavity
2. Olfactory receptor neurons are embedded in olfactory epithelium.
3. Olfactory receptors neurons send their projections via spinal cord to the olfactory thalamus.
4. Olfactory receptor neuron specificity originates from the specific olfactory receptor protein expressed in that receptor
5. Highest density of odorant receptors are found in the cilia

False:
3

Correct:

1. Olfactory receptor cells are neurons that line the upper portion of the nasal cavity
2. Olfactory receptor neurons are embedded in olfactory epithelium.

4. Olfactory receptor neuron specificity originates from the specific olfactory receptor protein expressed in that receptor
5. Highest density of odorant receptors are found in the cilia

Olfactory receptor neurons send their projections via cranial nerves. Unlike vision, somatosensation and vision (audition?) gustatory and olfactory stimuli do not reach a sensory modality specific nucleus in the thalamus.

What three distinct cell classes does the olfactory epithelium contain?

  1. Sensory neurons each with a primary cilium
  2. supporting cells between them
  3. basal cells that divide regularly producing sensory neurons
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Taste transduction takes place in papillae
Which four types of papillae are in the tongue?

The four types of papillae in the tongue:
  • Foliate papillae:
    • a series of folds along the sides of the tongue
  • Fungiform papillae:
    • mushroom shaped & found at the tip and sides of the tongue
  • Circumvallate papillae:
    • shaped like flat mounds surrounded by a trench & found at the back of the tongue
  • Filiform papillae:
    • cone shaped & found all over the tongue (which is why tongues look rough). Do not contain taste buds!

Molecular mechanism of taste transduction

Compared to olfactory transduction

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